Hypothermic Machine Preservation Benefits Deceased Donor Kidneys With Short Cold Ischemic Times
نویسندگان
چکیده
منابع مشابه
Machine perfusion or cold storage in deceased-donor kidney transplantation.
BACKGROUND Static cold storage is generally used to preserve kidney allografts from deceased donors. Hypothermic machine perfusion may improve outcomes after transplantation, but few sufficiently powered prospective studies have addressed this possibility. METHODS In this international randomized, controlled trial, we randomly assigned one kidney from 336 consecutive deceased donors to machin...
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In this edition of the Clinical Journal of the American Society of Nephrology, Gebel et al. (1) present simulation data showing that the new kidney allocation system (KAS) increases the offer rate for highly sensitizedkidney transplant candidates. This is counter to the previously held belief that the only possibility of transplanting a highly sensitized patient iswith anHLA-identical kidney. T...
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PURPOSE Marginal grafts should be used more actively in Asian countries where deceased donor transplantation is unpopular. We modified a quantitative donor scoring system proposed by Nyberg and his colleagues and developed a donor scoring system in order to assess the quality of deceased donor grafts and their prognostic value as an initial effort to promote usage of marginal donors. MATERIAL...
متن کاملReduced Expression of Inflammatory Genes in Deceased Donor Kidneys Undergoing Pulsatile Pump Preservation
BACKGROUND The use of expanded criteria donor kidneys (ECD) had been associated with worse outcomes. Whole gene expression of pre-implantation allograft biopsies from deceased donor kidneys (DDKs) was evaluated to compare the effect of pulsatile pump preservation (PPP) vs. cold storage preservation (CSP) on standard and ECD kidneys. METHODOLOGY/PRINCIPAL FINDINGS 99 pre-implantation DDK biops...
متن کاملHypothermic Machine Perfusion Preservation of the DCD Kidney: Machine Effects
Purpose. Kidneys from DCD donors represent a significant pool, but preservation problems exist. The study objective was to test the importance of machine type for hypothermic preservation of DCD kidneys. Methods. Adult Beagle dog kidneys underwent 45 minutes of warm in situ ischemia followed by hypothermic perfusion for 24 hours (Belzer-MPS Solution) on either an ORS LifePort or a Waters RM3 us...
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ژورنال
عنوان ژورنال: Transplantation
سال: 2018
ISSN: 0041-1337
DOI: 10.1097/tp.0000000000002187